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Differential growth triggers mechanical feedback that elevates Hippo signaling

Mechanical stress can influence cell proliferation in vitro, but whether it makes a significant contribution to growth control in vivo, and how it is modulated and experienced by cells within developing tissues, has remained unclear. Here we report that differential growth reduces cytoskeletal tensi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Pan, Yuanwang, Heemskerk, Idse, Ibar, Consuelo, Shraiman, Boris I., Irvine, Kenneth D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111668/
https://ncbi.nlm.nih.gov/pubmed/27791172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1615012113
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