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Cytoskeletal Tension inhibits Hippo signaling through an Ajuba-Warts complex

Mechanical forces have been proposed to modulate organ growth, but a molecular mechanism that links them to growth regulation in vivo has been lacking. We report that increasing tension within the cytoskeleton increases Drosophila wing growth, whereas decreasing cytoskeletal tension decreases wing g...

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Detalhes bibliográficos
Main Authors: Rauskolb, Cordelia, Sun, Shuguo, Sun, Gongping, Pan, Yuanwang, Irvine, Kenneth D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082802/
https://ncbi.nlm.nih.gov/pubmed/24995985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.05.035
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