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Regulation of Hippo signaling by EGFR-MAPK signaling through Ajuba family proteins
EGFR and Hippo signaling both control growth, and when dysregulated contribute to tumorigenesis. We find that EGFR activates the Hippo pathway transcription factor Yorkie, and demonstrate that Yorkie is required for the influence of EGFR on cell proliferation in Drosophila. EGFR regulates Yorkie thr...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3624988/ https://ncbi.nlm.nih.gov/pubmed/23484853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.01.020 |
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