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The flexibility and dynamics of protein disulfide isomerase

We have studied the mobility of the multidomain folding catalyst, protein disulfide isomerase (PDI), by a coarse‐graining approach based on flexibility. We analyze our simulations of yeast PDI (yPDI) using measures of backbone movement, relative positions and orientations of domains, and distances b...

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Détails bibliographiques
Publié dans:Proteins
Auteurs principaux: Römer, Rudolf A., Wells, Stephen A., Emilio Jimenez‐Roldan, J., Bhattacharyya, Moitrayee, Vishweshwara, Saraswathi, Freedman, Robert B.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111589/
https://ncbi.nlm.nih.gov/pubmed/27616289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25159
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