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Protein disulfide isomerases exploit synergy between catalytic and specific binding domains

Protein disulfide isomerases (PDIs) catalyse the formation of native disulfide bonds in protein folding pathways. The key steps involve disulfide formation and isomerization in compact folding intermediates. The high-resolution structures of the a and b domains of PDI are now known, and the overall...

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Autori principali: Freedman, Robert B., Klappa, Peter, Ruddock, Lloyd W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083976/
https://ncbi.nlm.nih.gov/pubmed/11839698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf035
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