Protein flexibility is key to cisplatin crosslinking in calmodulin

Chemical crosslinking in combination with Fourier transform ion cyclotron resonance mass spectrometry (FTICR MS) has significant potential for studying protein structures and protein–protein interactions. Previously, cisplatin has been shown to be a crosslinker and crosslinks multiple methionine (Me...

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Main Authors: Li, Huilin, Wells, Stephen A, Jimenez-Roldan, J Emilio, Römer, Rudolf A, Zhao, Yao, Sadler, Peter J, O'Connor, Peter B
Format: Artigo
Sprog:Inglês
Udgivet: Wiley Subscription Services, Inc., A Wiley Company 2012
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631356/
https://ncbi.nlm.nih.gov/pubmed/22733664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2111
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