Use of Top-down and Bottom-up Fourier Transform Ion Cyclotron Resonance Mass Spectrometry for Mapping Calmodulin Sites modified by Platinum Anticancer Drugs

Calmodulin (CaM) is a highly conserved, ubiquitous, calcium-binding protein; it binds to and regulates many different protein targets, thereby functioning as a calcium sensor and signal transducer. CaM contains 9 methionine (Met), 1 histidine (His), 17 aspartic acid (Asp), and 23 glutamine acid (Glu...

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Detalhes bibliográficos
Main Authors: Li, Huilin, Lin, Tzu-Yung, Van Orden, Steve L., Zhao, Yao, Barrow, Mark P., Pizarro, Ana M., Qi, Yulin, Sadler, Peter J., O’Connor, Peter B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237854/
https://ncbi.nlm.nih.gov/pubmed/22032417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac202267g
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