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Sequence-dependent attack on peptides by photoactivated platinum anticancer complexes
Octahedral platinum(iv) complexes such as trans,trans,trans-[Pt(N(3))(2)(OH)(2)(pyridine)(2)] (1) are stable in the dark, but potently cytotoxic to a range of cancer cells when activated by UVA or visible light, and active in vivo. Photoactivation causes the reduction of the complex and leads to the...
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| Publicado no: | Chem Sci |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5911824/ https://ncbi.nlm.nih.gov/pubmed/29732057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc05135b |
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