Complement inhibition enables tumor delivery of LCMV glycoprotein pseudotyped viruses in the presence of antiviral antibodies

The systemic delivery of therapeutic viruses, such as oncolytic viruses or vaccines, is limited by the generation of neutralizing antibodies. While pseudotyping of rhabdoviruses with the lymphocytic choriomeningitis virus glycoprotein has previously allowed for multiple rounds of delivery in mice, t...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Ther Oncolytics
मुख्य लेखकों: Evgin, Laura, Ilkow, Carolina S, Bourgeois-Daigneault, Marie-Claude, de Souza, Christiano Tanese, Stubbert, Lawton, Huh, Michael S, Jennings, Victoria A, Marguerie, Monique, Acuna, Sergio A, Keller, Brian A, Lefebvre, Charles, Falls, Theresa, Le Boeuf, Fabrice, Auer, Rebecca A, Lambris, John D, McCart, J Andrea, Stojdl, David F, Bell, John C
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2016
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111574/
https://ncbi.nlm.nih.gov/pubmed/27909702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2016.27
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