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Quantitative evaluation of the antiretroviral efficacy of dolutegravir

The second-generation HIV-1 integrase strand transfer inhibitor (InSTI) dolutegravir (DTG) has had a major impact on the treatment of HIV-1 infection. Here we describe important but previously undetermined pharmacodynamic parameters for DTG. We show that the dose-response curve slope, which indicate...

詳細記述

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書誌詳細
出版年:JCI Insight
主要な著者: Laskey, Sarah B., Siliciano, Robert F.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111505/
https://ncbi.nlm.nih.gov/pubmed/27882352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90033
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