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Quantitative evaluation of the antiretroviral efficacy of dolutegravir
The second-generation HIV-1 integrase strand transfer inhibitor (InSTI) dolutegravir (DTG) has had a major impact on the treatment of HIV-1 infection. Here we describe important but previously undetermined pharmacodynamic parameters for DTG. We show that the dose-response curve slope, which indicate...
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| Publicado no: | JCI Insight |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5111505/ https://ncbi.nlm.nih.gov/pubmed/27882352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90033 |
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