The Cytoplasmic Tail Domain of Epstein-Barr Virus gH Regulates Membrane Fusion Activity through Altering gH Binding to gp42 and Epithelial Cell Attachment

Epstein-Barr virus (EBV) is associated with infectious mononucleosis and a variety of cancers as well as lymphoproliferative disorders in immunocompromised patients. EBV mediates viral entry into epithelial and B cells using fusion machinery composed of four glycoproteins: gB, the gH/gL complex, and...

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Bibliographic Details
Published in:mBio
Main Authors: Chen, Jia, Jardetzky, Theodore S., Longnecker, Richard
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111410/
https://ncbi.nlm.nih.gov/pubmed/27935841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01871-16
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