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Mapping the N-Terminal Residues of Epstein-Barr Virus gp42 That Bind gH/gL by Using Fluorescence Polarization and Cell-Based Fusion Assays

Epstein-Barr virus (EBV) requires at a minimum membrane-associated glycoproteins gB, gH, and gL for entry into host cells. B-cell entry additionally requires gp42, which binds to gH/gL and triggers viral entry into B cells. The presence of soluble gp42 inhibits membrane fusion with epithelial cells...

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Main Authors: Liu, Fengling, Marquardt, Gaby, Kirschner, Austin N., Longnecker, Richard, Jardetzky, Theodore S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937788/
https://ncbi.nlm.nih.gov/pubmed/20668073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00381-10
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