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The Large Groove Found in the gH/gL Structure Is an Important Functional Domain for Epstein-Barr Virus Fusion

Epstein-Barr virus (EBV) mediates viral entry into cells using four glycoproteins—gB, the gH/gL complex, and gp42—and fusion is cell type specific. gB and gH/gL are required for epithelial cell fusion; B cell fusion also requires gp42. To investigate functional domains within the gH/gL structure, we...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Jia, Jardetzky, Theodore S., Longnecker, Richard
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624213/
https://ncbi.nlm.nih.gov/pubmed/23325693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03245-12
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