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TERT Promoter Mutations Enhance Telomerase Activation by Long-range Chromatin Interactions
While single nucleotide somatic mutations in the proximal promoter of the human telomerase reverse transcriptase (TERT) gene create novel consensus sequences for transcription factors that enhance TERT expression, the precise mechanism of how telomerase is re-activated in cancer cells remains poorly...
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| Publicado no: | Cancer Discov |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5111399/ https://ncbi.nlm.nih.gov/pubmed/27807101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-16-1050 |
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