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Complete Molecular Weight Profiling of Low-Molecular Weight Heparins Using Size Exclusion Chromatography-Ion Suppressor-High-Resolution Mass Spectrometry

Low-molecular weight heparins (LMWH) prepared by partial depolymerization of unfractionated heparin are used globally to treat coagulation disorders on an outpatient basis. Patent protection for several LMWH has expired and abbreviated new drug applications have been approved by the Food and Drug Ad...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Zaia, Joseph, Khatri, Kshitij, Klein, Joshua, Shao, Chun, Sheng, Yuewei, Viner, Rosa
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111364/
https://ncbi.nlm.nih.gov/pubmed/27709905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.6b03081
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