Ultraperformance ion-pairing liquid chromatography with on-line electrospray ion trap mass spectrometry for heparin disaccharide analysis

A high resolution method for the separation and analysis of disaccharides prepared from heparin and heparan sulfate (HS) using heparin lyases is described. Ultraperformance liquid chromatography in a reverse-phase, ion-pairing mode efficiently separates eight heparin/HS disaccharides. The disacchari...

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Main Authors: Yang, Bo, Weyers, Amanda, Baik, Jong Youn, Sterner, Eric, Sharfstein, Susan, Mousa, Shaker A., Zhang, Fuming, Dordick, Jonathan S., Linhardt, Robert J.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108029/
https://ncbi.nlm.nih.gov/pubmed/21530482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2011.04.003
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