Lack of direct evidence for natural selection at the candidate thrifty gene locus, PPARGC1A

BACKGROUND: The gene PPARGC1A, in particular the Gly482Ser variant (rs8192678), had been proposed to be subject to natural selection, particularly in recent progenitors of extant Polynesian populations. Reasons include high levels of population differentiation and increased frequencies of the derive...

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Bibliografske podrobnosti
izdano v:BMC Med Genet
Main Authors: Cadzow, Murray, Merriman, Tony R., Boocock, James, Dalbeth, Nicola, Stamp, Lisa K., Black, Michael A., Visscher, Peter M., Wilcox, Phillip L.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111290/
https://ncbi.nlm.nih.gov/pubmed/27846814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-016-0341-z
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