Lack of direct evidence for natural selection at the candidate thrifty gene locus, PPARGC1A

BACKGROUND: The gene PPARGC1A, in particular the Gly482Ser variant (rs8192678), had been proposed to be subject to natural selection, particularly in recent progenitors of extant Polynesian populations. Reasons include high levels of population differentiation and increased frequencies of the derive...

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Publicado en:BMC Med Genet
Autores principales: Cadzow, Murray, Merriman, Tony R., Boocock, James, Dalbeth, Nicola, Stamp, Lisa K., Black, Michael A., Visscher, Peter M., Wilcox, Phillip L.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111290/
https://ncbi.nlm.nih.gov/pubmed/27846814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-016-0341-z
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