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Intrinsic cellular signaling mechanisms determine the sensitivity of cancer cells to virus-induced apoptosis

Cancer cells of epithelial and mesenchymal phenotypes exhibit different sensitivities to apoptosis stimuli, but the mechanisms underlying this phenomenon remain partly understood. We constructed a novel recombinant adenovirus expressing Ad12 E1A (Ad-E1A12) that can strongly induce apoptosis. Ad-E1A1...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Wang, Yunfei, Li, Dawei, Luo, Jian, Tian, Guimei, Zhao, Lisa Y., Liao, Daiqing
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111159/
https://ncbi.nlm.nih.gov/pubmed/27849011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37213
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