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Reconstructing integrin activation in vitro

Integrin activation leads to an increased affinity for the extracellular matrix and regulates many cellular processes such as cell adhesion and migration. To capture the process of integrin inside-out activation in a purified system, we describe here methods to isolate platelet αIIbβ3 integrins in t...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Methods Mol Biol
Main Authors: Gingras, Alexandre R., Ye, Feng, Ginsberg, Mark H.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110568/
https://ncbi.nlm.nih.gov/pubmed/23868579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-538-5_1
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