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Reconstructing integrin activation in vitro

Integrin activation leads to an increased affinity for the extracellular matrix and regulates many cellular processes such as cell adhesion and migration. To capture the process of integrin inside-out activation in a purified system, we describe here methods to isolate platelet αIIbβ3 integrins in t...

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Bibliografiske detaljer
Udgivet i:Methods Mol Biol
Main Authors: Gingras, Alexandre R., Ye, Feng, Ginsberg, Mark H.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110568/
https://ncbi.nlm.nih.gov/pubmed/23868579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-538-5_1
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