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Reconstructing integrin activation in vitro

Integrin activation leads to an increased affinity for the extracellular matrix and regulates many cellular processes such as cell adhesion and migration. To capture the process of integrin inside-out activation in a purified system, we describe here methods to isolate platelet αIIbβ3 integrins in t...

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Détails bibliographiques
Publié dans:Methods Mol Biol
Auteurs principaux: Gingras, Alexandre R., Ye, Feng, Ginsberg, Mark H.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110568/
https://ncbi.nlm.nih.gov/pubmed/23868579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-538-5_1
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