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Reconstructing integrin activation in vitro
Integrin activation leads to an increased affinity for the extracellular matrix and regulates many cellular processes such as cell adhesion and migration. To capture the process of integrin inside-out activation in a purified system, we describe here methods to isolate platelet αIIbβ3 integrins in t...
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Publié dans: | Methods Mol Biol |
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Auteurs principaux: | , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
2013
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5110568/ https://ncbi.nlm.nih.gov/pubmed/23868579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-538-5_1 |
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