Amelioration of proteolipid protein 139–151-induced encephalomyelitis in SJL mice by modified amino acid copolymers and their mechanisms

Copolymer 1 [Cop1, glatiramer acetate, Copaxone, poly(Y,E,A,K)n] is widely used in the treatment of relapsing/remitting multiple sclerosis in which it reduces the frequency of relapses by ≈30%. In the present study, copolymers with modified amino acid compositions (based on the binding motif of myel...

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Detalhes bibliográficos
Main Authors: Stern, Joel N. H., Illés, Zsolt, Reddy, Jayagopala, Keskin, Derin B., Sheu, Eric, Fridkis-Hareli, Masha, Nishimura, Hiroyuki, Brosnan, Celia F., Santambrogio, Laura, Kuchroo, Vijay K., Strominger, Jack L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC511046/
https://ncbi.nlm.nih.gov/pubmed/15292514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403832101
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