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Distinct and overlapping functions of the cullin E3 ligase scaffolding proteins CUL4A and CUL4B
The cullin 4 subfamily of genes includes CUL4A and CUL4B, which share a mostly identical amino acid sequence aside from the elongated N-terminal region in CUL4B. Both act as scaffolding proteins for modular cullin RING ligase 4 (CRL4) complexes which promote the ubiquitination of a variety of substr...
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| Publicado no: | Gene |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5110433/ https://ncbi.nlm.nih.gov/pubmed/26344709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2015.08.064 |
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