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Kinase regulation of Human MHC Class I Molecule Expression on Cancer Cells

The major histocompatibility complex I (MHC-I) presents antigenic peptides to tumor-specific CD8(+) T cells. The regulation of MHC-I by kinases is largely unstudied, even though many patients with cancer are receiving therapeutic kinase inhibitors. Regulators of cell surface HLA amounts were discove...

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Bibliografski detalji
Izdano u:Cancer Immunol Res
Glavni autori: Brea, Elliott J., Oh, Claire Y., Manchado, Eusebio, Budhu, Sadna, S.Gejman, Ron, Mo, George, Mondello, Patrizia, Han, James E., Jarvis, Casey A., Ulmert, David, Xiang, Qing, Chang, Aaron Y., Garippa, Ralph J., Merghoub, Taha, Wolchok, Jedd D., Rosen, Neal, Lowe, Scott W., Scheinberg, David A.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110210/
https://ncbi.nlm.nih.gov/pubmed/27680026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-16-0177
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