Monitoring Integration over Time Supports a Role for Cytotoxic T Lymphocytes and Ongoing Replication as Determinants of Reservoir Size

The dynamics of HIV reservoir accumulation off antiretroviral therapy (ART) is underexplored. Levels of integrated HIV DNA in peripheral blood mononuclear cells (PBMCs) were longitudinally monitored before and after antiviral therapy. HIV integration increased over time in both elite controllers (EC...

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Opis bibliograficzny
Wydane w:J Virol
Główni autorzy: Pinzone, Marilia Rita, Graf, Erin, Lynch, Lindsay, McLaughlin, Brigit, Hecht, Frederick M., Connors, Mark, Migueles, Stephen A., Hwang, Wei-Ting, Nunnari, Giuseppe, O'Doherty, Una
Format: Artigo
Język:Inglês
Wydane: American Society for Microbiology 2016
Hasła przedmiotowe:
Pathogenesis and Immunity
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110192/
https://ncbi.nlm.nih.gov/pubmed/27630237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00242-16
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