Monitoring Integration over Time Supports a Role for Cytotoxic T Lymphocytes and Ongoing Replication as Determinants of Reservoir Size

The dynamics of HIV reservoir accumulation off antiretroviral therapy (ART) is underexplored. Levels of integrated HIV DNA in peripheral blood mononuclear cells (PBMCs) were longitudinally monitored before and after antiviral therapy. HIV integration increased over time in both elite controllers (EC...

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Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Pinzone, Marilia Rita, Graf, Erin, Lynch, Lindsay, McLaughlin, Brigit, Hecht, Frederick M., Connors, Mark, Migueles, Stephen A., Hwang, Wei-Ting, Nunnari, Giuseppe, O'Doherty, Una
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2016
Konular:
Pathogenesis and Immunity
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110192/
https://ncbi.nlm.nih.gov/pubmed/27630237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00242-16
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