Next-Generation Sequencing in a Direct Model of HIV Infection Reveals Important Parallels to and Differences from In Vivo Reservoir Dynamics

Next-generation sequencing (NGS) represents a powerful tool to unravel the genetic make-up of the HIV reservoir, but limited data exist on its use in vitro. Moreover, most NGS studies do not separate integrated from unintegrated DNA, even though selection pressures on these two forms should be disti...

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Bibliographic Details
Published in:J Virol
Main Authors: Pinzone, Marilia Rita, Bertuccio, Maria Paola, VanBelzen, D. Jake, Zurakowski, Ryan, O’Doherty, Una
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2020
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7163122/
https://ncbi.nlm.nih.gov/pubmed/32051279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01900-19
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