CD72 negatively regulates B lymphocyte responses to the lupus-related endogenous toll-like receptor 7 ligand Sm/RNP

Toll-like receptor 7 (TLR7) plays an essential role in development of systemic lupus erythematosus by co-stimulating B cells reactive to the endogenous TLR7 ligand Sm/ribonucleoprotein (RNP), a crucial lupus self-antigen. However, how the TLR7-mediated autoimmune response is regulated is not yet kno...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Akatsu, Chizuru, Shinagawa, Kenro, Numoto, Nobutaka, Liu, Zhihong, Ucar, Ayse Konuskan, Aslam, Mohammad, Phoon, Shirly, Adachi, Takahiro, Furukawa, Koji, Ito, Nobutoshi, Tsubata, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110020/
https://ncbi.nlm.nih.gov/pubmed/27810925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160560
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