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Tankyrase SAM domain polymerization is required for its role in Wnt signaling
Tankyrase-1 (TNKS1/PARP-5a) is a poly(ADP-ribose) polymerase (PARP) enzyme that regulates multiple cellular processes creating a poly(ADP-ribose) posttranslational modification that can lead to target protein turnover. TNKS1 thereby controls protein levels of key components of signaling pathways, in...
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| Publicado no: | Structure |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5109827/ https://ncbi.nlm.nih.gov/pubmed/27499439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.06.022 |
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