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Easy regulation of metabolic flux in Escherichia coli using an endogenous type I-E CRISPR-Cas system
BACKGROUND: Clustered regularly interspaced short palindromic repeats interference (CRISPRi) is a recently developed powerful tool for gene regulation. In Escherichia coli, the type I CRISPR system expressed endogenously shall be easy for internal regulation without causing metabolic burden in compa...
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| Publicat a: | Microb Cell Fact |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5109708/ https://ncbi.nlm.nih.gov/pubmed/27842593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-016-0594-4 |
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