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Tunable switch mediated shikimate biosynthesis in an engineered non-auxotrophic Escherichia coli

Shikimate is a key intermediate in the synthesis of neuraminidase inhibitors. Compared with traditional methods, microbial production of shikimate has the advantages of environmental friendliness, low cost, feed stock renewability, and product selectivity and diversity. Despite these advantages, shi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gu, Pengfei, Su, Tianyuan, Wang, Qian, Liang, Quanfeng, Qi, Qingsheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942831/
https://ncbi.nlm.nih.gov/pubmed/27406890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29745
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