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Tunable switch mediated shikimate biosynthesis in an engineered non-auxotrophic Escherichia coli

Shikimate is a key intermediate in the synthesis of neuraminidase inhibitors. Compared with traditional methods, microbial production of shikimate has the advantages of environmental friendliness, low cost, feed stock renewability, and product selectivity and diversity. Despite these advantages, shi...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Gu, Pengfei, Su, Tianyuan, Wang, Qian, Liang, Quanfeng, Qi, Qingsheng
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942831/
https://ncbi.nlm.nih.gov/pubmed/27406890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29745
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