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Molecular basis for cytoplasmic RNA surveillance by uridylation‐triggered decay in Drosophila
The posttranscriptional addition of nucleotides to the 3′ end of RNA regulates the maturation, function, and stability of RNA species in all domains of life. Here, we show that in flies, 3′ terminal RNA uridylation triggers the processive, 3′‐to‐5′ exoribonucleolytic decay via the RNase II/R enzyme...
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Publicado no: | EMBO J |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley and Sons Inc.
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5109242/ https://ncbi.nlm.nih.gov/pubmed/27729457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695164 |
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