Apoptosis Triggers Specific, Rapid, and Global mRNA Decay with 3′ Uridylated Intermediates Degraded by DIS3L2

Apoptosis is a tightly coordinated cell death program that damages mitochondria, DNA, proteins, and membrane lipids. Little is known about the fate of RNA as cells die. Here, we show that mRNAs, but not noncoding RNAs, are rapidly and globally degraded during apoptosis. mRNA decay is triggered early...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Thomas, Marshall P., Liu, Xing, Whangbo, Jennifer, McCrossan, Geoffrey, Sanborn, Keri B., Basar, Emre, Walch, Michael, Lieberman, Judy
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862650/
https://ncbi.nlm.nih.gov/pubmed/25959823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.04.026
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados