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Cav1.2 and Cav1.3 L‐type calcium channels independently control short‐ and long‐term sensitization to pain

KEY POINTS: L‐type calcium channels in the CNS exist as two subunit forming channels, Cav1.2 and Cav1.3, which are involved in short‐ and long‐term plasticity. We demonstrate that Cav1.3 but not Cav1.2 is essential for wind‐up. These results identify Cav1.3 as a key conductance responsible for short...

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書誌詳細
出版年:J Physiol
主要な著者: Radwani, Houda, Lopez‐Gonzalez, Maria José, Cattaert, Daniel, Roca‐Lapirot, Olivier, Dobremez, Eric, Bouali‐Benazzouz, Rabia, Eiríksdóttir, Emelía, Langel, Ülo, Favereaux, Alexandre, Errami, Mohammed, Landry, Marc, Fossat, Pascal
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108908/
https://ncbi.nlm.nih.gov/pubmed/27231046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272725
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