Bidirectional integrative regulation of Cav1.2 calcium channel by microRNA miR-103: role in pain

Chronic pain states are characterized by long-term sensitization of spinal cord neurons that relay nociceptive information to the brain. Among the mechanisms involved, up-regulation of Cav1.2-comprising L-type calcium channel (Cav1.2-LTC) in spinal dorsal horn have a crucial role in chronic neuropat...

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Main Authors: Favereaux, Alexandre, Thoumine, Olivier, Bouali-Benazzouz, Rabia, Roques, Virginie, Papon, Marie-Amélie, Salam, Sherine Abdel, Drutel, Guillaume, Léger, Claire, Calas, André, Nagy, Frédéric, Landry, Marc
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173784/
https://ncbi.nlm.nih.gov/pubmed/21804529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.249
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