Touchscreen Learning Deficits and Normal Social Approach Behavior in the Shank3B Model of Phelan–Mcdermid Syndrome and Autism

SHANK3 is a synaptic scaffolding protein localized in the postsynaptic density and has a crucial role in synaptogenesis and neural physiology. Deletions and point mutations in SHANK3 cause Phelan–McDermid Syndrome (PMS), and have also been implicated in autism spectrum disorder (ASD) and intellectua...

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Detalhes bibliográficos
Publicado no:Neuroscience
Main Authors: Copping, Nycole A., Berg, Elizabeth L., Foley, Gillian M., Schaffler, Melanie D., Onaga, Beth L., Buscher, Nathalie, Silverman, Jill L., Yang, Mu
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108683/
https://ncbi.nlm.nih.gov/pubmed/27189882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2016.05.016
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