Retinal safety of intravitreal rtPA in healthy rats and under excitotoxic conditions

PURPOSE: Intravitreal recombinant tissue plasminogen activator (rtPA) is used off-label for the surgical management of submacular hemorrhage, a severe complication of neovascular age-related macular degeneration. rtPA is approved for coronary and cerebral thrombolysis. However, in ischemic stroke rt...

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Publicado en:Mol Vis
Autores principales: Daruich, Alejandra, Parcq, Jérôme, Delaunay, Kimberley, Naud, Marie-Christine, Le Rouzic, Quentin, Picard, Emilie, Crisanti, Patricia, Vivien, Denis, Berdugo, Marianne, Behar-Cohen, Francine
Formato: Artigo
Lenguaje:Inglês
Publicado: Molecular Vision 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108461/
https://ncbi.nlm.nih.gov/pubmed/27881907
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