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Combination of ultrasound and rtPA enhances fibrinolysis in an In Vitro clot system

BACKGROUND: Catheter-based lysis with recombinant tissue plasminogen activator (rtPA) is a well-established therapy for spontaneous intracerebral hemorrhage (ICH). The effectiveness of this therapy can be increased with ultrasound, but the optimal conditions are not yet clearly established. Using a...

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Bibliographic Details
Published in:PLoS One
Main Authors: Masomi-Bornwasser, Julia, Winter, Philipp, Müller-Werkmeister, Hendrik, Strand, Susanne, König, Jochem, Kempski, Oliver, Ringel, Florian, Kantelhardt, Sven R., Keric, Naureen
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5690612/
https://ncbi.nlm.nih.gov/pubmed/29145482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188131
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