Retinal safety of intravitreal rtPA in healthy rats and under excitotoxic conditions

PURPOSE: Intravitreal recombinant tissue plasminogen activator (rtPA) is used off-label for the surgical management of submacular hemorrhage, a severe complication of neovascular age-related macular degeneration. rtPA is approved for coronary and cerebral thrombolysis. However, in ischemic stroke rt...

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Bibliographic Details
Published in:Mol Vis
Main Authors: Daruich, Alejandra, Parcq, Jérôme, Delaunay, Kimberley, Naud, Marie-Christine, Le Rouzic, Quentin, Picard, Emilie, Crisanti, Patricia, Vivien, Denis, Berdugo, Marianne, Behar-Cohen, Francine
Format: Artigo
Language:Inglês
Published: Molecular Vision 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108461/
https://ncbi.nlm.nih.gov/pubmed/27881907
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