Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk

To identify risk variants for multiple myeloma (MM), we conducted a genome-wide association study totaling of 1,675 MM cases and 5,903 controls. We identified risk loci for MM at 3p22.1 (rs1052501, ULK4; odds ratio [OR]=1.32; P=7.47x10(-9)) and 7p15.3 (rs4487645, OR=1.38; P=3.33x10(-15)). In additio...

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Publicado no:Nat Genet
Main Authors: Broderick, Peter, Chubb, Daniel, Johnson, David C, Weinhold, Niels, Försti, Asta, Lloyd, Amy, Olver, Bianca, Ma, Yussanne, Dobbins, Sara E, Walker, Brian A, Davies, Faith E, Gregory, Walter A, Childs, J. Anthony, Ross, Fiona M, Jackson, Graham H, Neben, Kai, Jauch, Anna, Hoffmann, Per, Mühleisen, Thomas W, Nöthen, Markus M, Moebus, Susanne, Tomlinson, Ian P, Goldschmidt, Hartmut, Hemminki, Kari, Morgan, Gareth J, Houlston, Richard S
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108406/
https://ncbi.nlm.nih.gov/pubmed/22120009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.993
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