Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk

To identify variants for multiple myeloma risk, we conducted a genome-wide association study with validation in additional series totaling 4,692 cases and 10,990 controls. We identified four risk loci at 3q26.2 (rs10936599, P=8.70x10(-14)), 6p21.33 (rs2285803, PSORS1C2; P= 9.67x10(-11)), 17p11.2 (rs...

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Vydáno v:Nat Genet
Hlavní autoři: Chubb, Daniel, Weinhold, Niels, Broderick, Peter, Chen, Bowang, Johnson, David C, Försti, Asta, Vijayakrishnan, Jayaram, Migliorini, Gabriele, Dobbins, Sara E, Holroyd, Amy, Hose, Dirk, Walker, Brian A, Davies, Faith E, Gregory, Walter A, Jackson, Graham H, Irving, Julie A, Pratt, Guy, Fegan, Chris, Fenton, James AL, Neben, Kai, Hoffmann, Per, Nöthen, Markus M, Mühleisen, Thomas W, Eisele, Lewin, Ross, Fiona M, Straka, Christian, Einsele, Hermann, Langer, Christian, Dörner, Elisabeth, Allan, James M, Jauch, Anna, Morgan, Gareth J, Hemminki, Kari, Houlston, Richard S, Goldschmidt, Hartmut
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053356/
https://ncbi.nlm.nih.gov/pubmed/23955597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2733
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