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The SIRT2 deacetylase stabilizes Slug to control malignancy of basal-like breast cancer

Overabundance of Slug protein is common in human cancer and represents an important determinant underlying the aggressiveness of basal-like breast cancer (BLBC). Despite its importance, this transcription factor is rarely mutated in BLBC, and the mechanism of its deregulation in cancer remains unkno...

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Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Zhou, Wenhui, Ni, Thomas K., Wronski, Ania, Glass, Benjamin, Skibinski, Adam, Beck, Andrew, Kuperwasser, Charlotte
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108094/
https://ncbi.nlm.nih.gov/pubmed/27783945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.10.006
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