Design, Synthesis, and Cytotoxic Evaluation of Novel Tubulysin Analogues as ADC Payloads

[Image: see text] The tubulysin class of natural products has attracted much attention from the medicinal chemistry community due to its potent cytotoxicity against a wide range of human cancer cell lines, including significant activity in multidrug-resistant carcinoma models. As a result of their p...

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Xehetasun bibliografikoak
Argitaratua izan da:ACS Med Chem Lett
Egile Nagusiak: Leverett, Carolyn A., Sukuru, Sai Chetan K., Vetelino, Beth C., Musto, Sylvia, Parris, Kevin, Pandit, Jayvardhan, Loganzo, Frank, Varghese, Alison H., Bai, Guoyun, Liu, Bin, Liu, Dingguo, Hudson, Sarah, Doppalapudi, Venkata Ramana, Stock, Joseph, O’Donnell, Christopher J., Subramanyam, Chakrapani
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2016
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108041/
https://ncbi.nlm.nih.gov/pubmed/27882198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00274
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