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Effects of Single α-to-β Residue Replacements on Structure and Stability in a Small Protein: Insights from Quasiracemic Crystallization

Synthetic peptides that contain backbone modifications but nevertheless adopt folded structures similar to those of natural polypeptides are of fundamental interest and may provide a basis for biomedical applications. Such molecules can, for example, mimic the ability of natural prototypes to bind t...

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Vydáno v:J Am Chem Soc
Hlavní autoři: Kreitler, Dale F., Mortenson, David E., Forest, Katrina T., Gellman, Samuel H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107306/
https://ncbi.nlm.nih.gov/pubmed/27171550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b01454
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