Identification of Novel Inhibitors against Coactivator Associated Arginine Methyltransferase 1 Based on Virtual Screening and Biological Assays

Overexpression of coactivator associated arginine methyltransferase 1 (CARM1), a protein arginine N-methyltransferase (PRMT) family enzyme, is associated with various diseases including cancers. Consequently, the development of small-molecule inhibitors targeting PRMTs has significant value for both...

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Bibliografiska uppgifter
I publikationen:Biomed Res Int
Huvudupphovsmän: Ye, Fei, Zhang, Weiyao, Lu, Wenchao, Xie, Yiqian, Jiang, Hao, Jin, Jia, Luo, Cheng
Materialtyp: Artigo
Språk:Inglês
Publicerad: Hindawi Publishing Corporation 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107250/
https://ncbi.nlm.nih.gov/pubmed/27872854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7086390
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