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Application of amide hydrogen/deuterium exchange mass spectrometry for epitope mapping in human cystatin C
Human cystatin C (hCC) is a small cysteine protease inhibitor whose oligomerization by propagated domain swapping is linked to certain neurological disorders. One of the ways to prevent hCC dimerization and fibrillogenesis is to enable its interaction with a proper antibody. Herein, the sites of int...
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| Veröffentlicht in: | Amino Acids |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer Vienna
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5107209/ https://ncbi.nlm.nih.gov/pubmed/27573935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-016-2316-y |
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