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The Phenol-ene Reaction: Biaryl Synthesis via Trapping Reactions between HDDA-Generated Benzynes and Phenolics

Benzynes produced thermally by the cycloisomerization of triyne-containing precursors [i.e., by the hexadehydro-Diels–Alder (HDDA) reaction] react with phenols at the carbon ortho to the hydroxyl in an ene-like fashion. Following tautomerization of the intermediate cyclohexadienones, this produces b...

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Publicat a:Org Lett
Autors principals: Zhang, Juntian, Niu, Dawen, Brinker, Vincent A., Hoye, Thomas R.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107112/
https://ncbi.nlm.nih.gov/pubmed/27767316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b02830
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