A carregar...
Distinct downstream targets manifest p53-dependent pathologies in mice
Mdm2, the principal negative regulator of p53, is critical for survival, a fact clearly demonstrated by the p53-dependent death of germline or conditional mice following deletion of Mdm2. On the other hand, Mdm2 hypomorphic (Mdm2(Puro/Δ7 − 12)) or heterozygous (Mdm2(+/−)) mice that express either 30...
Na minha lista:
| Publicado no: | Oncogene |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5106874/ https://ncbi.nlm.nih.gov/pubmed/27065327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.111 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|